Ortho-Selective Side-Chain Nitration of Methyl-Substituted Alkenoylbenzenes and Its Application to Synthesis of 4-Nitro-1-tetralones
Methyl-substituted alkenoylbenzenes 1a-m involving acryoyl, methacryloyl, β-(ethoxycarbonyl)acryloyl, crotonoyl, and cinnamoyl groups as alkenoyl functions reacted with fuming nitric acid in acetic anhydride to give 2-(nitromethyl)alkenoylbenzenes 2a-m in