Conventional and microwave induced synthesis of various azetidinone and thiazolidinone derivatives from 3-[(1E)-1-aza-2-(2-chloro-7-methoxy-3-quinolyl) vinyl]-4-(aryldiazenyl) phenol and their antimicrobial screening
3-Chloro-4-(2-chloro-7-methoxy-3-quinolyl)-1-[3-hydroxy-6-(aryldiazenyl) phenyl] azetidin-2-one 2 and 2-(2-chloro7-methoxy-3-quinolyl)-3-[3-hydroxy-6- (aryldiazenyl) phenyl]-1, 3-thiazolidin-4-one 3 have been synthesized by the reaction of 3-[(1E)-1-aza-2-(2-chloro-7-methoxy-3-quinolyl)-vinyl]-4- (aryldiazenyl) phenol 1 with chloroacetylchloride and mercapto acetic acid, respectively. Both the reactions have been carried out by conventional and microwave methods. These compounds have been screened for their antibacterial, antifungal and antitubercular activity against different microorganisms.
Patel, Jigisha A.,Mistry,Desai
experimental part
p. 1695 - 1700
(2009/07/11)
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