- ANTHRAQUINONES AND FLAVONOIDS OF CASSIA LAEVIGATA ROOTS
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Key Word Index -- Cassia laevigata; Leguminosae roots; physcion 8-galactoside; emodin; physcion; ombuin; anthraquinones; flavonoids.
- Singh, .,Tiwari, A. R.,Tiwari, R. D.
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- Antibacterial activity of a triterpenoid saponin from the stems of Caesalpinia pulcherrima Linn.
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A new compound 1 was isolated from the methanolic extract of the stems of the Caesalpinia pulcherrima Linn. along with a reported compound (2) 3-O-β-D-glucopyranosyl-(1→4)-β-D-xylopyranosyl-(1→3)-α-L-rhamnopyranosyl-(1→2)-α-L-arabinopyranosyl hederagenin 28-O-β-D-glucopyranosyl-(1→6)-β-D-glucopyranosyl ester. The new compound 1 has m.p. 272–274°C, m.f. C46H74O17, [M]+ m/z 898. It was characterised as 3-O-β-D-glucopyranosyl-(1→4)-α-L-arabinopyranosyl hederagenin 28-O-β-D- xylopyranosyl ester by various colour reactions, chemical degradations and spectral analyses. Antibacterial activity of compound 1 was screened against various Gram-positive and Gram-negative bacteria and showed significant results.
- Asati, Nidhi,Yadava
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p. 499 - 507
(2017/09/30)
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- Characterization of a novel polysaccharide with anti-colon cancer activity from Lactobacillus helveticus MB2-1
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The present study aimed at investigating the potential anti-colon cancer activity of three purified exopolysaccharides fractions (LHEPS-1, LHEPS-2 and LHEPS-3) from the Lactobacillus helveticus MB2-1. The experimental evidence showed that LHEPS-1 significantly inhibited cell proliferation of human colon cancer Caco-2 cells in both time- and concentration-dependent manners. In contrast, no significant improvements of the inhibitory effects of LHEPS-2 and LHEPS-3 on Caco-2 cells were observed with increasing sample concentrations or prolonged incubation time. Furthermore, the structure of LHEPS-1 was elucidated using methylated analysis, gas chromatography-mass spectroscopy (GC-MS) and nuclear magnetic resonance spectroscopy (NMR), including one- and two-dimensional nuclear magnetic resonance (1D and 2D NMR). Results indicated that the LHEPS-1 consisted of a decasaccharide repeating unit with the following structure (n≈122): Our results suggested that the LHEPS-1 produced by L. helveticus MB2-1 might be suitable for using as natural anti-colon cancer drugs and functional foods ingredients.
- Li, Wei,Tang, Weizhi,Ji, Juan,Xia, Xiudong,Rui, Xin,Chen, Xiaohong,Jiang, Mei,Zhou, Jianzhong,Dong, Mingsheng
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- Microwave-accelerated methylation of starch
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A novel microwave-accelerated method for methylating soluble starch is described. Soluble starch could be fully methylated in 72% yield within 4.66 min using iodomethane and 30% potassium hydroxide under microwave irradiation. The completely methylated starch thus obtained was hydrolyzed with 60% HCO2H for 1.5 min under 80% MW power, followed by 0.05 M H2SO4 for 2.0 min under 100% MW power. The partially methylated monosaccharides were separated by preparative paper chromatography and identified by their melting points and optical rotations.
- Singh, Vandana,Tiwari, Ashutosh
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p. 151 - 154
(2008/09/18)
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- Sulfenate intermediates in the sulfoxide glycosylation reaction
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The sulfoxide glycosylation reaction works remarkably well for many difficult glycosylations. We attribute this in part to the fact that an extremely reactive intermediate can be generated rapidly under mild conditions at low temperature. We find that ano
- Gildersleeve, Jeff
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p. 5961 - 5969
(2007/10/03)
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- New Phenolic Components from Dalbergia Volubilis
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Phytochemical examination of non green branches of Dalbergia volubilis on extensive column and preparative thin layer chromatography yielded twelve compounds eight of which are already known compounds and were identified as sitosterol, 7-hydroxy-4-methyl-coumarin, dalbergin, biochanin-A, umbelliferone, p-hydroxy cinnamic acid, kaempferol and quercetin-3-O-glucoside.The other four compounds were new natural products, three of which were identified as novel 4-phenyl-2H-1-benzopyran-2-ones while the fourth one was a new 12a-hydroxy rotenoid.The structure of these new compounds has been established on the basis of chemical and spectral evidences and through derivatization, as 4',7-dihydroxy-3'-methoxy-4-phenyl-2H-1-benzopyran-2-one, 3',7-dihydroxy-4',5-dimethoxy-2H-1-benzopyran-2-one, 3',7-dihydroxy4',5-dimethoxy-6-formyl-2H-1-benzopyran-2-one and a complex rotenoid determined to be as (VII).The co-occurence of 4-methyl-2H-1-benzopyran-2-ones, 4-phenyl-2H-1-benzopyran-2-ones, isoflavones and rotenoids is of interest from biogenetic considerations.
- Chawla, H. Mohindra,Johny, C. J.,Mittal, Ram S.
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- TRITERPENE GLYCOSIDES OF Salsola micranthera. II. THE STRUCTURE OF SALSOLOSIDE E
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A new triterpene glycoside - salsoloside E - has been isolated from the epigeal part of the plant Salsola micranthera Botsch. family Chenopodiaceae.On the basis of chemical transformations and physicochemical characteristics its structure has been established as oleanoic acid 28-O-β-D-glucopyranoside 3-O-2)>4)>-β-D-glucuronopyranoside>.
- Annaev, Ch.,Isamukhamedova, M.,Abubakirov, N. K.
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- CLEAVAGE OF INTERGLYCOSIDIC LINKAGES IN PER(TRIMETHYLSILYL)ATED AND PERMETHYLATED CARBOHYDRATES WITH IODOTRIMETHYLSILANE
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Iodotrimethylsilane in carbon tetrachloride cleaves interglycosidic linkages in per(trimethylsilyl)ated disaccharides to give iodinolysis products that may be readily hydrolyzed to component monosaccharides.The cleavage rate is dependent on the type of interglycosidic linkage, and is in the order (1->4)2)3)6) for derivatives of β-linked glucobioses.This iodinolysis reagent is more reactive toward interglycosidic linkages in permethylated carbohydrates; all of the linkages in the permethylated derivatives examined were completely cleaved, irrespective of linkage type.Iodinolysis with iodotrimethylsilane, followed by treatment of the products with water, offers a rapid and mild method for hydrolysis of permethylated carbohydrates.
- Honda, Susumu,Ichii, Tsunehiko,Kakehi, Kazuaki
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- THREE ISOFLAVONE GLYCOSIDES FROM JUNIPERUS MACROPODA
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Three new isoflavone glycosides have been characterized from the leaves of Juniperus macropoda: 5,7-dihydroxy-6,3',4'-trimethoxyisoflavone 7-glucoside; 5,7,4'-trihydroxy-6,3',5'-trimethoxyisoflavone glucoside and 5,7,3'-trihydroxy-6,4'-dimethoxyisoflavone 7-diglucoside.Key Word Index - Juniperus macropoda; Cupressaceae; leaves; isoflavone glycosides.
- Sethi, M. L.,Taneja, S. C.,Dhar, K. L.,Atal, C. K.
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p. 289 - 292
(2007/10/02)
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- NIVYASIDE - A NEW GLYCOSIDE FROM Leucanthemum vulgare
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From the ligulate flowers of Leucanthemum vulgare Lam. growing on the territory of the Georgian SSR a new glycoside has been isolated which has been called nivyaside and has the structure 8-(1-α-D-glucopyranosyl-5-deoxyquercit-5-yl)-4',5,7-trihydroxyflavone.
- Sagareishvili, T. G.,Alaniya, M. D.,Kikoladze, V. S.,Kemertelidze, E. P.
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p. 408 - 412
(2007/10/02)
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- 1,2,3-TRIOXYGENATED GLUCOSYLOXYXANTHONES FROM POLYGALA TRIPHYLLA
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Key Word Index - Polygala triphylla; Polygalaceae; xanthones; 1,2,3-trioxygenated xanthone; 1,2,3,6,7-pentaoxygenated xanthone; glucosyloxyxanthone; 1-glucosyloxy-2-hydroxy-3-methoxyxanthone; 1-glucosyloxy-2,3-methylenedioxyxanthone. Four B-ring oxygen-free trioxygenated xanthones, viz. 1-OH-2,3-(OMe)2-, 1,2,3-(OMe)3-, 1-OH-2,3-(OCH2O)-, 1-OMe-2,3-(OCH2O)-xanthone, two B-ring oxygen-free glucosyloxyxanthones, viz. 1-O-gl.-2-OH-3-OMe- and 1-O-gl.-2,3-(OCH2O)-xanthone, and a pentaoxygenated xanthone, 1-OMe-2,3,6,7-(OCH2O)xanthone, have been isolated from the flowering top of Polygala triphylla.The xanthones have been characterized on the basis of chemical transformation, comprehensive spectral evidence, and by direct comparison where possible.This is the first report of occurrence of the glucosyloxyxanthones in nature.The biochemical significance of these chemical characters in higher plants is appraised.
- Ghosal, Shibnat,Basumatari, Prasad C.,Banerjee, Shanta
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p. 489 - 492
(2007/10/02)
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- ACETOLYSIS OF Leukonostoc mesenteroides NRRL B-1299 DEXTRAN. ISOLATION AND CHARACTERIZATION OF OLIGOSACCHARIDES CONTAINING SECONDARY LINKAGES FROM THE BORATE-SOLUBLE FRACTION
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Fractionation of the deacetylated acetolyzate of the borate-soluble fraction of the dextran elaborated by Leuconostoc mesenteroides MRRL B-1299 gave, after chromatography on charcoal-Celite, preparative paper-chromatography, and paper electrophoresis, four trisaccharide fractions and four tetrasaccharide fractions.The isolated oligosaccharides were characterized by their paper-chromatographic mobility, examination of partial acid-hydrolyzates of the oligosaccharides and their corresponding alditols, and methylation analysis.These oligosaccharides were shown to be (a) kojitriose (1), (b) isomaltotriose (2), (c) a mixture of 2-O-α-isomaltosyl-D-glucose (3), 21-O-α-D-glucosylisomaltose (4), and 2-O-α-nigerosyl-D-glucose (5), (d) 6-O-α-kojibiosyl-D-glucose (6), (e) isomaltotetraose (7), (f) a mixture of 2-O-α-isomaltotriosyl-D-glucose (8) and 21-O-α-D-glycosylisomaltotriose (9), (g) 6-O-α-kojitriosyl-D-glucose (10), and (h) 63-O-α-D-glucosylkojitriose (11), respectively.Some of these oligosaccharides are newly isolated and characterized.
- Watanabe, Toshiyuki,Chiba, Michiko,Matsuda, Yutaka,Sakurai, Fukuko,Kobayashi, Mikihiko,Matsuda, Kazuo
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p. 119 - 128
(2007/10/02)
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- XANTHONE AND FLAVONOL CONSTITUENTS OF SWERTIA HOOKERI
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The whole plant of Swertia hookeri, collected at flowering has been shown to contain two tri- and nine tetraoxygenated free, glucosyloxy, and stearyl ester xanthones and one flavonol stearyl ester.Among these, three are previously unreported in nature and one was known previously only as a synthetic compound.The xanthones are based on 1,3,5-, 1,3,5,8- and 1,3,7,8-oxygenated systems with the middle oxygenation pattern predominating.The two ester compounds appeared only at the flowering stage.Plants collected at the pre-flowering stage gave the corresponding free compounds.The biochemical and biological significance of these findings are appraised.Key Word Index - Swertia hookeri; Gentianaceae; 1-O-stearyl-3,5-dimethoxyxanthone; 3-O-stearyl-3',4',5,7-tetra-O-methylquercetin; 1-hydroxy-3,5-dimethoxyxanthone; tetraoxygenated xanthones; 8-O-β-D-glucosyl-1,3-dihydroxy-5-methoxyxanthones; 8-O-β-D-glucosyl-1,5-dihydroxy-3-methoxyxanthone.
- Ghosal, Shibnath,Biswas, Kanika,Jaiswal, Dinesh K.
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p. 123 - 126
(2007/10/02)
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- TOMATOSIDE A FROM THE SEEDS OF Lycopersicum esculentum
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Results are given which confirm the structure of the furostanol glycoside from tomato seeds forming wastes of the preserving industry.From a butanolic extract of the seeds of Lycopersicum esculentum Mill. we have isolated the furostanol glycoside tomatoside A (I) the structure of which has been established as 25(S)-5α-furostan-3β,22α,26-triol 26-O-β-D-glucopyranoside 3-O2)-O-β-D-glucopyranosyl-(1->4)-β-D-galactopyranoside>.At the same time, by enzymatic and chemical transformations three new spirostanol glycosides of neotigogenin have been obtained: tomatoside B (III), which is 25(S)-5α-spirostan-3β-ol 3-O-2)-β-D-galactopyranoside>, 25(S)-5α-spirostan-3β-ol 3-O-4)-β-D-galactopyranoside> (V), and 25(S)-5α-spirostan-3β-ol 3-O-β-D-galactopyranoside (IV).
- Shchelochkova, A. P.,Vollerner, Yu. S.,Koshoev, K. K.
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p. 386 - 392
(2007/10/02)
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- ISOCAVIUNIN 7-GENTIOBIOSIDE, A NEW ISOFLAVONE GLYCOSIDE FROM DALBERGIA SISSOO
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Key Word Index - Dalbergia sissoo; Leguminosae; isoflavone; isocaviunin-7-O-β-(1-->6)-diglucoside.
- Sharma, Anil,Chibber, S. S.,Chawla, H. M.
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