114214-45-8 Usage
Main Properties
1. Chemical Formula: C7H6F3NO
2. Physical State: Colorless to pale yellow liquid
3. Primary Use: Intermediate in organic synthesis
4. Specific Applications: Used in pharmaceutical and agrochemical production
5. Secondary Use: Building block in the synthesis of dyes and specialty chemicals
6. Reactivity: Unique reactivity and selectivity due to trifluoroaniline group
7. Safety Concerns: Handle with caution; harmful if swallowed, inhaled, or absorbed through the skin; can cause irritation to skin, eyes, and respiratory system.
Check Digit Verification of cas no
The CAS Registry Mumber 114214-45-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,4,2,1 and 4 respectively; the second part has 2 digits, 4 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 114214-45:
(8*1)+(7*1)+(6*4)+(5*2)+(4*1)+(3*4)+(2*4)+(1*5)=78
78 % 10 = 8
So 114214-45-8 is a valid CAS Registry Number.
114214-45-8Relevant articles and documents
COMPOUNDS FOR THE TREATMENT OF BRAF-ASSOCIATED DISEASES AND DISORDERS
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Paragraph 0975; 0977, (2021/01/20)
Provided herein are compounds of the Formula I: and pharmaceutically acceptable salts, solvates and polymorphs thereof, wherein L, X1, R1, R2, R3, R4, R5 and R6 are as defined herein, for the treatment of BRAF-associated diseases and disorders, including BRAF-associated tumors, including malignant and benign BRAF-associated tumors of the CNS and malignant extracranial BRAF-associated tumors.
Quinoline-3-carboxylic acid derivatives
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, (2008/06/13)
Compounds of formula (I): STR1 (in which R1 is alkoxy, R is alkyl, haloalkyl, alkylamino, cycloalkyl or optionally substituted phenyl, X is chlorine or fluorine and Y is selected from certain specific heterocycles) have excellent antibacterial activity. They may be prepared by introducing the group represented by Y into the corresponding compound in which Y is replaced by a halogen atom.
