Certain 1H-pyrrold[3,4-b]quinolin-1-one-9-amino-2,3-dihydro derivatives useful for treating anxiety
The present invention comprises certain quinoline lactams of formula I; pharmaceutically acceptable salts of the compounds of formula I; pharmaceutical compositions containing a compound of formula I, or a pharmaceutically acceptable salt thereof, for use in the treatment of anxiety; and processes for the manufacture of the compounds of formula I, as well as intermediates for use in such manufacture.
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(2008/06/13)
FACILE PALLADIUM-CATALYZED CROSS-COUPLING OF MONOORGANOZINC HALIDES WITH 3-IODOANTHRANILONITRILES
A convenient synthesis of 3-substituted anthranilonitriles has been developed which involves cross-coupling of monoorganozinc halides with 3-iodoanthranilonitrile catalyzed by a palladium complex.
Campbell, James B.,Firor, Judy Wawerchak,Davenport, Timothy W.
p. 2265 - 2272
(2007/10/02)
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