114417-85-5

Basic information

• Product Name: 2-Piperazineaceticacid,3,6-dioxo-,methylester,(2S)-(9CI)
• Synonyms: 2-Piperazineaceticacid,3,6-dioxo-,methylester,(2S)-(9CI);METHYL [(2S)-3,6-DIOXOPIPERAZIN-2-YL]ACETATE
• CAS NO: 114417-85-5
• Molecular Formula: C7 H10 N2 O4
• Molecular Weight: 186.17
• Product Categories: PIPERIDINE
• Mol File: 114417-85-5.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-Piperazineaceticacid,3,6-dioxo-,methylester,(2S)-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Piperazineaceticacid,3,6-dioxo-,methylester,(2S)-(9CI)(114417-85-5)
• EPA Substance Registry System: 2-Piperazineaceticacid,3,6-dioxo-,methylester,(2S)-(9CI)(114417-85-5)

Safety Data

• Hazardous Substances Data: 114417-85-5(Hazardous Substances Data)

Upstream product

• 4685-12-5 glycyl-L-aspartic acid 
• 17343-03-2 N-glycyl-D-Asp 

Relevant articles and documents

Synthesis of glutaryl-containing derivatives of GRGD and KRGD peptides

New derivatives of tetrapeptides GRGD (Gly-Arg(Pbf)-Gly-Asp(OMe)-OMe) and KRGD (Boc-Lys-Arg(Pbf)-Gly-Asp(OMe)-OMe) containing a glutaric acid fragment as a linker were synthesized. The linker provides the possibility for binding these derivatives to other biologically active molecules or nanoparticles.

Process for preparing diketopiperazine derivatives

A diketopiperazine derivative is prepared by reacting chloroacetylaspartic acid with ammonia water, diesterifying the resulting glycyl-aspartic acid with an alkanol, and then cyclizing the diester in neutral or weakly basic water or in an alkanol-water solvent mixture.