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1144853-59-7

2-[(4-Methoxybenzyl)-2-oxo-5-(thiomorpholinosulfonyl)indolin-3-ylidene]malononitrile is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 2-[(4-Methoxybenzyl)-2-oxo-5-(thiomorpholinosulfonyl)indolin-3-ylidene]malononitrile

    Cas No: 1144853-59-7

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  • 2-[(4-Methoxybenzyl)-2-oxo-5-(thiomorpholinosulfonyl)indolin-3-ylidene]malononitrile

    Cas No: 1144853-59-7

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  • 1144853-59-7 Structure

  • Basic information

    1. Product Name: 2-[(4-Methoxybenzyl)-2-oxo-5-(thiomorpholinosulfonyl)indolin-3-ylidene]malononitrile
    2. Synonyms: 2-[(4-Methoxybenzyl)-2-oxo-5-(thiomorpholinosulfonyl)indolin-3-ylidene]malononitrile;2-[1,2-Dihydro-1-[(4-Methoxyphenyl)Methyl]-2-oxo-5-(4-thioMorpholinylsulfonyl)-3H-indol-3-ylidene]propanedinitrile
    3. CAS NO:1144853-59-7
    4. Molecular Formula: C23H20N4O4S2
    5. Molecular Weight: 494.54282
    6. EINECS: N/A
    7. Product Categories: Amines;Aromatics;Heterocycles;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals;Sulfur & Selenium Compounds
    8. Mol File: 1144853-59-7.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 2-[(4-Methoxybenzyl)-2-oxo-5-(thiomorpholinosulfonyl)indolin-3-ylidene]malononitrile(CAS DataBase Reference)
    10. NIST Chemistry Reference: 2-[(4-Methoxybenzyl)-2-oxo-5-(thiomorpholinosulfonyl)indolin-3-ylidene]malononitrile(1144853-59-7)
    11. EPA Substance Registry System: 2-[(4-Methoxybenzyl)-2-oxo-5-(thiomorpholinosulfonyl)indolin-3-ylidene]malononitrile(1144853-59-7)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1144853-59-7(Hazardous Substances Data)

1144853-59-7 Usage

Uses

Isatin sulfonamide analog as Caspase-3 inhibitors.

Check Digit Verification of cas no

The CAS Registry Mumber 1144853-59-7 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,4,4,8,5 and 3 respectively; the second part has 2 digits, 5 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1144853-59:
(9*1)+(8*1)+(7*4)+(6*4)+(5*8)+(4*5)+(3*3)+(2*5)+(1*9)=157
157 % 10 = 7
So 1144853-59-7 is a valid CAS Registry Number.

1144853-59-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-[1-[(4-methoxyphenyl)methyl]-2-oxo-5-thiomorpholin-4-ylsulfonylindol-3-ylidene]propanedinitrile

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

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More Details:1144853-59-7 SDS

1144853-59-7Downstream Products

1144853-59-7Relevant articles and documents

Synthesis and in vitro evaluation of sulfonamide isatin Michael acceptors as small molecule inhibitors of caspase-6

Chu, Wenhua,Rothfuss, Justin,Chu, Yunxiang,Zhou, Dong,Mach, Robert H.

supporting information; experimental part, p. 2188 - 2191 (2010/03/03)

A key step in the onset of Huntington's disease is the caspase-6 mediated cleavage of the protein huntingtin into toxic fragments. Therefore, the inhibition of caspase-6 has been identified as a target for therapeutic drug development for the treatment of

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