114525-81-4

Basic information

• Product Name: (R)-4-BOC-THIOMORPHOLINE-3-CARBOXYLIC ACID
• Synonyms: 3,4-Thiomorpholinedicarboxylic acid, 4-(1,1-dimethylethyl) ester, (3R)-;(R)-N-BOC-THIOMORPHOLINE-3-CARBOXYLIC ACID;R-ThioMorpholine-3,4-dicarboxylic acid 4-tert-butyl ester;(R)-4-BOC-THIOMORPHOLINE-3-CARBOXYLIC ACID;(R)-4-(TERT-BUTOXYCARBONYL)-THIOMORPHOLINE-3-CARBOXYLIC ACID;(R)-BOC-3-CARBOXYTHIOMORPHOLINE
• CAS NO: 114525-81-4
• Molecular Formula: C₁₀H₁₇NO₄S
• Molecular Weight: 247.31
• Mol File: 114525-81-4.mol

Chemical Properties

• Boiling Point: 398.6°C at 760 mmHg
• Flash Point: 194.8°C
• Appearance: /
• Density: 1.259g/cm³
• Vapor Pressure: 1.82E-07mmHg at 25°C
• Refractive Index: 1.534
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• PKA: 3.53±0.20(Predicted)
• CAS DataBase Reference: (R)-4-BOC-THIOMORPHOLINE-3-CARBOXYLIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-4-BOC-THIOMORPHOLINE-3-CARBOXYLIC ACID(114525-81-4)
• EPA Substance Registry System: (R)-4-BOC-THIOMORPHOLINE-3-CARBOXYLIC ACID(114525-81-4)

Safety Data

• Hazardous Substances Data: 114525-81-4(Hazardous Substances Data)

Usage

Uses

Used in Organic Synthesis:
(R)-4-BOC-THIOMORPHOLINE-3-CARBOXYLIC ACID is used as a reagent for the protection of amines, enabling selective reactions to occur at other sites on the molecule. This selective protection is crucial in complex organic synthesis processes, where specific functional groups need to be temporarily masked to prevent unwanted reactions.
Used in Pharmaceutical Research:
(R)-4-BOC-THIOMORPHOLINE-3-CARBOXYLIC ACID is used as a building block for the synthesis of various pharmaceuticals and bioactive compounds. Its unique structure and the presence of the BOC protecting group make it a valuable component in the development of new drugs with potential therapeutic applications.
Used in Peptide-based Drug Preparation:
(R)-4-BOC-THIOMORPHOLINE-3-CARBOXYLIC ACID serves as a starting material for the preparation of peptide-based drugs. The BOC group can be selectively removed under mild conditions, allowing for the formation of peptide bonds and the synthesis of peptide-based therapeutic agents.

InChI:InChI=1/C10H17NO4S/c1-10(2,3)15-9(14)11-4-5-16-6-7(11)8(12)13/h7H,4-6H2,1-3H3,(H,12,13)

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 65527-54-0 2-(R)-thiomorpholine carboxylic acid hydrochloride 

Downstream Products

• 253153-07-0 C₂₇H₃₁Cl₂N₃O₆S 
• 1228968-53-3 (R)-N-Boc-thiomorpholine-3-carboxylic acid 
• 78865-47-1 methyl (3R)-1,4-thiazane-3-carboxylate 
• 65527-54-0 2-(R)-thiomorpholine carboxylic acid hydrochloride 
• 1445981-26-9 (R)-(4-cyclopropyl-3,4-dihydroquinoxaline-1(2H)-yl)(4-(2,5-dichlorobenzyl) thiomorpholin-3-yl)methanone 
• 1436423-27-6 (R)-tert-butyl 3-(4-(4-chloro-2-(4-(3,3,3-trifluoropropyl)piperazin-1-yl)phenylcarbamoyl)-2,3-difluorobenzylcarbamoyl)thiomorpholine-4-carboxylate 
• 253155-08-7 C₃₀H₃₇Cl₂N₃O₆S 

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