114785-18-1Relevant articles and documents
Synthesis and Structure-Activity Relationships of a Novel Series of Non-Peptide Angiotensin II Receptor Binding Inhibitors Specific for the AT2 Subtype
Blankley, C. John,Hodges, John C.,Klutchko, Sylvester R.,Himmelsbach, Richard J.,Chucholowski, Alexander,et al.
, p. 3248 - 3260 (2007/10/02)
Structure-activity relationships are reported for a novel class of 4,5,6,7-tetrahydro-1H-imidazopyridine-6-carboxylic acid derivatives that displace 125I-labeled angiotensin II from a specific subset of angiotensin II (Ang II) binding sites in rat
4,5,6,7-TETRAHYDRO-1H-IMIDAZO(4,5-C)PYRIDINE-6-CARBOXYLIC ACID ANALOGS HAVING ANTIHYPERTENSIVE ACTIVITY
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, (2008/06/13)
This invention relates to novel substituted derivatives of 4,5, 6,7-tetrahydro-1H-imidazo[4,5-c]pyridine-6-carboxylic acid and analogs thereof, which are useful for the treatment of hypertension, as well as, novel pharmaceutical compositions and methods of use.