1150114-75-2

Basic information

• Product Name: 6-pyrrolidin-1-yl- pyridineboronic acid
• Synonyms: 6-pyrrolidin-1-yl- pyridineboronic acid;6-(Pyrrolidin-1-yl)pyridine-3-boronic acid;(2-Pyrrolidin-1-yl)pyridine-6-boronic acid;Boronic acid, B-[6-(1-pyrrolidinyl)-3-pyridinyl]-
• CAS NO: 1150114-75-2
• Molecular Formula: C₉H₁₃BN₂O₂
• Molecular Weight: 192.02272
• EINECS: -0
• Mol File: 1150114-75-2.mol

Chemical Properties

• Boiling Point: 421.3 °C at 760 mmHg
• Flash Point: 208.6 °C
• Appearance: /
• Density: 1.25 g/cm³
• PKA: 4.28±0.17(Predicted)
• CAS DataBase Reference: 6-pyrrolidin-1-yl- pyridineboronic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 6-pyrrolidin-1-yl- pyridineboronic acid(1150114-75-2)
• EPA Substance Registry System: 6-pyrrolidin-1-yl- pyridineboronic acid(1150114-75-2)

Safety Data

• Hazardous Substances Data: 1150114-75-2(Hazardous Substances Data)

Usage

Uses

Used in Organic Synthesis:
6-pyrrolidin-1-yl-pyridineboronic acid is used as a reagent in the Suzuki-Miyaura cross-coupling reaction, a widely employed method for forming carbon-carbon bonds. Its participation in this reaction facilitates the creation of new chemical entities, contributing to the advancement of organic synthesis techniques.
Used in Pharmaceutical Development:
In the pharmaceutical industry, 6-pyrrolidin-1-yl-pyridineboronic acid is utilized as a key intermediate in the synthesis of various drug molecules. Its unique structure allows for the development of compounds with novel therapeutic properties, enhancing the discovery of new medications for treating various diseases.
Used in Agrochemicals:
6-pyrrolidin-1-yl-pyridineboronic acid also finds application in the agrochemical sector, where it serves as a precursor in the synthesis of pesticides and other agrochemical products. Its reactivity and structural features enable the creation of effective compounds for crop protection and enhancement of agricultural productivity.
Used in Materials Science:
In the field of materials science, 6-pyrrolidin-1-yl-pyridineboronic acid is employed in the development of new materials with specific properties. Its integration into material compositions can lead to the creation of innovative materials with applications in various industries, such as electronics, energy, and nanotechnology.

Upstream product

• 121-43-7 Trimethyl borate 
• 210963-93-2 5-bromo-2-(pyrrolidin-1-yl)pyridine 

Downstream Products

• 1222878-32-1 N-(5-methyl-1,2-oxazol-3-yl)-2-[1-({3-[6-(pyrrolidin-1-yl)pyridin-3-yl]phenyl}methyl)-1H-indole-3-sulfonyl]acetamide 

Relevant articles and documents

Nitrogen-containing compound, electronic element and electronic device

The invention provides a nitrogen-containing compound, an electronic component and an electronic device, and relates to the technical field of organic materials, wherein the nitrogen-containing compound is represented by a formula I, X is selected from oxygen and sulfur, R is selected from heterocycloalkyl and heteroaryl, L is selected from a single bond, arylene and heteroarylene, the substituentof R is selected from deuterium, nitro, hydroxyl, alkyl, cycloalkyl, alkenyl, alkynyl, aryl, heteroaryl, heterocycloalkyl, alkoxy, aryl silyl and alkyl silyl, and the substituent of L is selected from deuterium, nitro, hydroxyl, alkyl, cycloalkyl, alkenyl, alkynyl, heterocycloalkyl, alkoxy, alkylsilyl, arylsilyl, aryloxy and arylthio. The nitrogen-containing compound disclosed by the invention can reduce the working voltage of an electronic component, improve the efficiency of a device and prolong the service life of the device.

SUBSTITUTED PYRIDOPYRAZINES AS NOVEL SYK INHIBITORS

Provided are pyridopyrazine compounds of formula (1), pharmaceutical compositions thereof and methods of use therefore, wherein R1, R2, R3, R4 and m are as defined in the specification.

SUBSTITUTED PYRIDOPYRAZINES AS NOVEL SYK INHIBITORS

Provided are certain pyridopyrazine compounds, pharmaceutical compositions thereof and methods of use therefor.