A convenient enantiospecific route towards bioactive merosesquiterpenes by cationic-resin-promoted Friedel-Crafts alkylation with α,β-enones
An enantiospecific route towards bioactive merosesquiterpenes, based on the cationic-resin-promoted Friedel-Crafts alkylation of alkoxyarenes with an α,β-unsaturated ketone, is reported. Reaction of ketone 11 with 3,4-methylenedioxyphenol afforded the cor