115103-10-1

Basic information

• Product Name: 1H-Benzimidazole-2-methanamine,5-nitro-(9CI)
• Synonyms: 1H-Benzimidazole-2-methanamine,5-nitro-(9CI)
• CAS NO: 115103-10-1
• Molecular Formula: C8H8N4O2
• Molecular Weight: 192.17472
• Product Categories: BENZIMIDAZOLE
• Mol File: 115103-10-1.mol

Chemical Properties

• Boiling Point: 486.7±25.0 °C(Predicted)
• Appearance: /
• Density: 1.514±0.06 g/cm3(Predicted)
• PKA: 11.81±0.29(Predicted)
• CAS DataBase Reference: 1H-Benzimidazole-2-methanamine,5-nitro-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Benzimidazole-2-methanamine,5-nitro-(9CI)(115103-10-1)
• EPA Substance Registry System: 1H-Benzimidazole-2-methanamine,5-nitro-(9CI)(115103-10-1)

Safety Data

• Hazardous Substances Data: 115103-10-1(Hazardous Substances Data)

Upstream product

• 99-56-9 4-Nitrophenylene-1,2-diamine 
• 14625-39-9 2-(chloromethyl)-6-nitro-1H-benzo[d]imidazole 

Relevant articles and documents

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A series of squaramido-tethered bisbenzimidazoles were synthesized from the reaction of diethyl squarate with substituted 2-aminomethylbenzimidazoles. These conjugates exhibit moderate binding affinity toward chloride anions. They are able to facilitate the transmembrane transport of chloride anions most probably via an anion exchange process, and tend to be more active at acidic pH than at physiological pH. The viability of these conjugates toward four selected solid tumor cell lines was evaluated using an MTT assay and the results suggest that some of these conjugates exhibit moderate cytotoxicity probably in an apoptotic fashion.

Dibenzimidazole conjugates with pH dependent anion trans-membrane transport activity Synthesis method and synthesis method thereof (by machine translation)

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