Structure-activity relationships among benextramine-related tetraamine disulfides. Chain length effect on α-adrenoreceptor blocking activity
Several N'-substituted N,N''-(dithiodi-2,1-ethanediyl)bis(1,ω-alkanediamines) were prepared and evaluated for their blocking activity on α-adrenoreceptors in the isolated rat vas deferens and human blood platelets. The results were compared with those obt