A concise synthesis of biaryl PDE4D allosteric modulators
The optimization and synthesis of biaryl PDE4D allosteric modulator D159687 was achieved on gram scale via a concise two-step process. The synthesis features sequential chemoselective Suzuki coupling reactions taking advantage of different reactivity prof
Dalby, Amy,Mo, Xuesheng,Stoa, Robert,Wroblewski, Nathaniel,Zhang, Zheng,Hagen, Timothy J.
p. 2737 - 2739
(2013/06/05)
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