Synthesis of hairpin siRNA using 18β-glycyrrhetinic acid derivative as a loop motif
We synthesized a new phosphoramidite building block from 18β-glycyrrhetinic acid. This compound was introduced in the middle of the palindromic oligonucleotides and they formed hairpin structure. This 18β-glycyrrhetinic acid derivative excellently perform
Bang, Eun-Kyoung,Kim, Byeang Hyean
supporting information; experimental part
p. 2545 - 2547
(2009/09/05)
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