COENZYME MODELS. PART 45. SYNTHESIS OF ATROPISOMERIC FLAVINS AND THEIR NOVEL REDOX-INDUCED RACEMISATION
Seven (5-carba)isoalloxazines with restricted rotation about the C(1')-N(10) single bond were synthesized for the first time.They were optically resolved by a liquid chromatographic method.Six of these atropisomers (92.1-100 percent enantiomeric excess) (