Synthesis and antiviral evaluation of alkoxyalkyl derivatives of 9-(S)-(3-hydroxy-2-phosphonomethoxypropyl)adenine against cytomegalovirus and orthopoxviruses
9-(S)-(3-Hydroxy-2-phosphonomethoxypropyl)adenine [(S)-HPMPA] was one of the first acyclic nucleoside phosphonates described and has been reported to have good antiviral activity against most double-stranded DNA viruses, including the herpes group viruses
Beadle, James R.,Wan, William B.,Ciesla, Stephanie L.,Keith, Kathy A.,Hartline, Caroll,Kern, Earl R.,Hosteller, Karl Y.
p. 2010 - 2015
(2007/10/03)
A convienient synthesis of S-HPMPA
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Webb II,Martin
p. 4963 - 4964
(2007/10/02)
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