- Syntheses of 2H-labelled dihydropyrimidinediones and their metabolites
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Starting with uracil or thymine, [5,5,6,6-2H4]-dihydrouracil and [5,6,6,α,α,α,-2H6]-dihydrothymine were synthesised in high yields by catalytic deuteriation. Subsequent hydrolyses resulted in the corresponding β-ureidoalkanoic acids and β-aminoacids.
- Heinkele, Georg,Hofmann, Ute,Opitz, Joachim,Muerdter, Thomas E.
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