1163123-39-4

Basic information

• Product Name: 2-chloro-4-fluorobenzo[d]oxazole
• Synonyms: 2-chloro-4-fluorobenzo[d]oxazole;Benzoxazole, 2-chloro-4-fluoro-
• CAS NO: 1163123-39-4
• Molecular Formula: C7H3ClFNO
• Molecular Weight: 171.5562232
• EINECS: -0
• Mol File: 1163123-39-4.mol

Chemical Properties

• Boiling Point: 206.9±13.0 °C(Predicted)
• Appearance: /
• Density: 1.482±0.06 g/cm3(Predicted)
• Storage Temp.: Inert atmosphere,Store in freezer, under -20°C
• PKA: -1.89±0.30(Predicted)
• CAS DataBase Reference: 2-chloro-4-fluorobenzo[d]oxazole(CAS DataBase Reference)
• NIST Chemistry Reference: 2-chloro-4-fluorobenzo[d]oxazole(1163123-39-4)
• EPA Substance Registry System: 2-chloro-4-fluorobenzo[d]oxazole(1163123-39-4)

Safety Data

• Hazardous Substances Data: 1163123-39-4(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Research:
2-chloro-4-fluorobenzo[d]oxazole is used as a building block for the development of new drugs, contributing to the advancement of medicinal chemistry and drug discovery. Its unique structural properties and reactivity make it a promising candidate for creating innovative pharmaceutical compounds.
Used in Organic Synthesis:
In the field of organic synthesis, 2-chloro-4-fluorobenzo[d]oxazole is utilized as a reagent in the preparation of various compounds. Its ability to participate in substitution and condensation reactions allows for the creation of a wide range of chemical products, further expanding its applications across different industries.

InChI:InChI=1S/C7H3ClFNO/c8-7-10-6-4(9)2-1-3-5(6)11-7/h1-3H

Upstream product

• 1163123-40-7 4-fluorobenzo[d]oxazole-2-thiol 

Relevant articles and documents

HETEROARYL DERIVATIVES AS OREXIN RECEPTOR ANTAGONISTS

The present invention relates to compounds of formula wherein Ar, Het, R1 and n are as defined herein and to pharmaceutically suitable acid addition salts, optically pure enantiomers, racemates or diastereomeric mixtures thereof. Compounds of formula I are orexin receptor antagonists and are useful in the treatment of sleep apnea, narcolepsy, insomnia, parasomnia, jet lag syndrome, circadian rhythms disorder and sleep disorders associated with neurological diseases.