- 2,4-diaminobutyric acid derivative and preparation method thereof
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The invention relates to a 2,4-diaminobutyric acid derivative and a preparation method thereof and relates to the field of medicine synthesis. An aspartic acid derivative serves as an initiator, and the 2,4-diaminobutyric acid derivative is obtained through simple reduction and substitution reaction. Different from the prior art, a reagent adopted for the method is small in toxicity, reaction conditions are mild, requirements for a device are not high, synthesis steps are simple, the 2,4-diaminobutyric acid derivative can be obtained at a high total yield, and the 2,4-diaminobutyric acid derivative facilitates large-scale industrial production and can be well applied to medicine synthesis.
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Paragraph 0047; 0048; 0049
(2017/07/20)
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- Synthesis of a cyclen-functionalized α-amino acid and its incorporation into peptide sequence
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A cyclen-functionlized α-amino acid was obtained through embedding cyclen into the side chain of homoserine. The α-amino acid can be conveniently incorporated into peptide sequence to form new ligands, which have strong coordination ability for transition metal ions. Georg Thieme Verlag Stuttgart.
- Chen, Shan-Yong,Huang, Yu,Zhang, Guo-Lin,Cheng, Hua,Xia, Chuan-Qin,Ma, Li-Jian,Yu, Hong,Yu, Xiao-Qi
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p. 888 - 892
(2007/10/03)
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