116399-78-1 Usage
Uses
Used in Organic Synthesis:
((E)-3-CHLORO-1-METHYLPROPENYL)TRIMETHYLSILANE is used as an alkylative agent for regiospecific enolate alkylation under nonequilibrating conditions. This application is particularly useful in organic synthesis, allowing for precise control over the reaction and the formation of specific products.
Used in Robinson Annulation:
In the field of organic chemistry, ((E)-3-CHLORO-1-METHYLPROPENYL)TRIMETHYLSILANE is used as an alkylative equivalent in Robinson annulation. This method is employed in the preparation of bicyclodecenones, as demonstrated by the alkylation of dihydrocarvone with this reagent.
Used in Combination with Potassium Iodide:
((E)-3-CHLORO-1-METHYLPROPENYL)TRIMETHYLSILANE has also been used in combination with potassium iodide for specific applications in organic chemistry, although these uses have been limited so far.
Overall, ((E)-3-CHLORO-1-METHYLPROPENYL)TRIMETHYLSILANE is a versatile compound in the field of organic synthesis, particularly for enolate alkylation and Robinson annulation reactions. Its applications are mainly focused on the synthesis of complex organic molecules and the development of novel chemical methodologies.
Check Digit Verification of cas no
The CAS Registry Mumber 116399-78-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,6,3,9 and 9 respectively; the second part has 2 digits, 7 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 116399-78:
(8*1)+(7*1)+(6*6)+(5*3)+(4*9)+(3*9)+(2*7)+(1*8)=151
151 % 10 = 1
So 116399-78-1 is a valid CAS Registry Number.
InChI:InChI=1/C7H15ClSi/c1-7(5-6-8)9(2,3)4/h5H,6H2,1-4H3/b7-5+
116399-78-1Relevant articles and documents
A succinct method for preparing the Stork-Jung vinylsilane Robinson annulation reagent
Singletary, Jeananne A.,Lam, Hubert,Dudley, Gregory B.
, p. 739 - 741 (2005)
(Chemical Equation Presented) The Stork-Jung vinylsilane reagent (1) is prepared in two steps and in good overall yield. This provides rapid and efficient access to a useful methyl vinyl ketone surrogate.
