- Synthesis of 2-aminophenols and heterocycles by Ru-catalyzed C-H mono- and dihydroxylation
-
A novel and efficient synthesis of 2-aminophenols, 2-aminobenzene-1,3- diols, and heterocycles through Ru-catalyzed C-H mono- and dihydroxylation of anilides has been developed with a new directing group strategy. The reaction demonstrates excellent reactivity, regioselectivity, good functional group tolerance, and high yields.
- Yang, Xinglin,Shan, Gang,Rao, Yu
-
supporting information
p. 2334 - 2337
(2013/07/04)
-
- Biarylalkanoic acids as cell adhesion inhibitors
-
Compounds of Formula I are antagonists of VLA-4 and/or α4β7, and as such are useful in the inhibition or prevention of cell adhesion and cell-adhesion mediated pathologies. These compounds may be formulated into pharmaceutical compositions and are suitable for use in the treatment of asthma, allergies, inflammation, multiple sclerosis, and other inflammatory and autoimmune disorders.
- -
-
-