cas 116680-01-4, 2-morpholin-4-ylethyl (E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1H-isobenzofuran-5-yl)-4-methyl-hex-4-enoate hydrochloride | Articles data ｜lookchem

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116680-01-4

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USAGE OF MYCOPHENOLATE MOFETIL OR SALT THEREOF IN PREPARING DRUG FOR RESISTING AGAINST INFLUENZA VIRUS
The present invention relates to a use of mycophenolate mofetil or a pharmaceutically acceptable salt thereof in the manufacture of a medicament against influenza virus. The present invention also relates to a use of mycophenolate mofetil or a pharmaceutically acceptable salt thereof in the manufacture of a medicament against drug-resistant influenza virus strains. The present invention is further related to a method for treating influenza in a subject, comprising administering to said subject an effective amount of mycophenolate mofetil or a pharmaceutically acceptable salt thereof.
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Paragraph 0048

(2016/03/14)

PROCESS FOR THE PRODUCTION OF MYCOPHENOLATE MOFETIL
The present invention relates to a new and economically attractive process for the production of mycophenolate mofetil in a high degree of pharmaceutically acceptable purity, which comprises the reaction of a reactive derivative of mycophenolic acid with 4-(2-hydroxyethyl)morpholine under acidic reaction conditions and the subsequent extraction of the pure mycophenolate mofetil through salt formation and release of the free base. A further aspect of the invention relates to the purification of mycophenolate mofetil by removing its by products, in particular its dimeric by-products, by means of treatment with a primary or secondary amine.
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Page/Page column 14

(2010/02/11)

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115007-34-6
mycophenolate mofetil

Chemical Properties

Melting Point: 154-155 °C
Boiling Point: 637.6°Cat760mmHg
Flash Point:339.4°C
Density: 1.222g/cm³
Vapor Pressure: 7.51E-17mmHg at 25°C
PSA: 94.53000
LogP: 3.26390

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