116870-85-0

Basic information

• Product Name: 3-(2-amino-3,6-dimethylphenyl)-2-[2-(diethylamino)ethyl]-2,3-dihydro-1H-isoindol-1-one dihydrochloride
• CAS NO: 116870-85-0
• Molecular Formula: C₂₂H₃₁Cl₂N₃O
• Molecular Weight: 424.407
• Mol File: 116870-85-0.mol

Chemical Properties

• Boiling Point: 493.5°C at 760 mmHg
• Flash Point: 252.2°C
• Vapor Pressure: 7.03E-10mmHg at 25°C
• CAS DataBase Reference: 3-(2-amino-3,6-dimethylphenyl)-2-[2-(diethylamino)ethyl]-2,3-dihydro-1H-isoindol-1-one dihydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(2-amino-3,6-dimethylphenyl)-2-[2-(diethylamino)ethyl]-2,3-dihydro-1H-isoindol-1-one dihydrochloride(116870-85-0)
• EPA Substance Registry System: 3-(2-amino-3,6-dimethylphenyl)-2-[2-(diethylamino)ethyl]-2,3-dihydro-1H-isoindol-1-one dihydrochloride(116870-85-0)

Safety Data

• Hazardous Substances Data: 116870-85-0(Hazardous Substances Data)

Relevant articles and documents

Isoindolin-1-one derivative and antiarrhythmic agent

Isoindolin-1-one compounds represented by the following formula (I); STR1 {wherein n represents an integer of 1 to 6; m represents 0 or 1; R1, R2 and R3 are each independently hydrogen or lower alkyl, and when m is 1, R1 and one of R2 and R3 may form a five-membered or six-membered ring over N atom; X represents hydrogen or hydroxy; Ar represents naphthyl, pyridyl or substituted phenyl represented by the formula (II); Ar and X may form a lactone ring; STR2 [wherein Y represents carboxyl, lower alkoxycarbonyl, carbamoyl, N,N-lower alkyl-substituted carbamoyl or amino represented by the formula (III): STR3 (wherein R6 and R7 are each independently hydrogen, lower alkyl or lower alkanoyl); R4 and R5 are each independently hydrogen, lower alkyl, cyano or halogen]} or a pharmaceutically acceptable acid addition salt or metal salt thereof have an excellent antiarrhythmic activity.