Derives de l'isocyanate de chlorosulfonyle. Synthese, structure et activite biologique d'halogeno-2 ethoxycarbonylsulfamides
New 2-chloroethoxycarbonylsulfamides are synthesized in a two step reaction from C.S.I., haloethanol and various primary and secondary amines.Cyclization of these sulfamides in basic medium gives the corresponding sulfamyl-oxazolidinones.All structures are established by IR, NMR, MS and RX diffraction data.The antitumor activity of the products towards LI210 is reported.