C-1,C-2 Stereospecific Rearrangements of Aldohexoses by Calcium Ion in Basic Solution
In aqueous or methanolic solution containing Ca(2+) and hydroxide ion, aldoses are rapidly epimerized at C-2.This reaction involves C-1,C-2 stereospecific rearrangement. -D-Mannose is formed from -D-glucose by this reaction.