Iridium-catalyzed highly enantioselective ring opening reaction of oxabenzonorbornadienes with amines
The complex of [Ir(COD)Cl]2 and (R)-xylyl-phanephos was used as an effective catalyst for the asymmetric ring opening reaction of oxabenzonorbornadienes with various amines. Under the optimized reaction conditions, high enantioselectivities with moderate to good yields could be obtained from a wild scope of oxabenzonorbornadienes and amines.
Palladacycle as highly efficient catalyst for ring opening of oxabicyclic alkenes with organozinc halides
Ring opening reaction of oxabicylic alkenes 4 with in situ prepared organozinc halides 5 was catalyzed by palladacycle 3 with high efficiency. Good yields of the corresponding 1,2-dihydronaphth-1-ols (6) were provided when as low as 0.05 mol% of palladacycle 3 was used. 31P NMR study showed that the skeleton of 3 remained intact in the reaction, which implied that palladacycle 3 did not serve as a catalyst precursor but a catalyst in the reaction.
Zhang, Ting-Ke,Yuan, Ke,Hou, Xue-Long
p. 1912 - 1919
(2007/10/03)
More Articles about upstream products of 117157-37-6