117258-21-6Relevant articles and documents
5-aryl-3H-1,2,4-triazol-3-ones and their use in the treatment of neurodegenerative disorders
-
, (2008/06/13)
This invention relates to neuroprotective 5-aryl-3H-1,2,4-triazol-3-ones and to their use in the treatment of neurodegenerative disorders such as cerebral ischemia, stroke, Alzheimer's disease, Parkinson's disease, and Huntington's disease.
2,4-Dihydro-3H-1,2,4-triazol-3-ones as anticonvulsant agents
Kane,Baron,Dudley,Sorensen,Staeger,Miller
, p. 2772 - 2777 (2007/10/02)
A series of 5-aryl-2,4-dihydro-3H-1,2,4-triazol-3-ones was evaluated for anticonvulsant activity. In general the members of this series were prepared by the alkaline crystalization of 1-aroyl-4-alkylsemicarbazides. The resulting 2-unsubstituted 3H-1,2,4-t