Synthesis of conjugates of 2′,3′-dideoxynucleoside-5′- monophosphates with α-amino acids
Previously undescribed conjugates of 2′,3′-dideoxyuridine- 5′-monophosphate-(L)-methoxytryptophylphosphoramidate (5) and 2′,3′-dideoxycytidine-5′-monophosphate-(L)- methoxytryptophylphosphoramidate (7) were isolated by a chemical enzymatic method in order to study their pharmacological properties and to prepare new medicinal preparations based on them. 2006 Springer Science+Business Media, Inc.