117832-09-4

Basic information

• Product Name: 2,4-DIIODO-6-METHYLBENZENAMINE
• Synonyms: 2,4-DIIODO-6-METHYLBENZENAMINE;2,4-Diiodo-6-Methylaniline
• CAS NO: 117832-09-4
• Molecular Formula: C₇H₇I₂N
• Molecular Weight: 358.94612
• Mol File: 117832-09-4.mol

Chemical Properties

• Boiling Point: 346.2 °C at 760 mmHg
• Flash Point: 163.1 °C
• Appearance: /
• Density: 2.359 g/cm³
• CAS DataBase Reference: 2,4-DIIODO-6-METHYLBENZENAMINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4-DIIODO-6-METHYLBENZENAMINE(117832-09-4)
• EPA Substance Registry System: 2,4-DIIODO-6-METHYLBENZENAMINE(117832-09-4)

Safety Data

• Hazardous Substances Data: 117832-09-4(Hazardous Substances Data)

Usage

Uses

Used in Organic Synthesis:
2,4-DIIODO-6-METHYLBENZENAMINE is used as an intermediate in organic synthesis for the production of a variety of compounds, leveraging its unique structure to facilitate the creation of complex organic molecules.
Used in Pharmaceutical Production:
In the pharmaceutical industry, 2,4-DIIODO-6-METHYLBENZENAMINE serves as a key intermediate, contributing to the development of new drugs due to its reactive functional groups and potential biological activity.
Used in Dye Manufacturing:
2,4-DIIODO-6-METHYLBENZENAMINE is utilized in the production of dyes, where its aromatic structure and iodine atoms provide specific color characteristics and properties to the final dye products.
Used in Agrochemicals:
2,4-DIIODO-6-METHYLBENZENAMINE is also employed in the agrochemical sector, where it may be used as a precursor to develop new pesticides or other agricultural chemicals that can improve crop protection and yield.
Used in Anti-Inflammatory and Antimicrobial Applications:
2,4-DIIODO-6-METHYLBENZENAMINE has been studied for its potential anti-inflammatory and antimicrobial properties, indicating its possible use in the development of treatments for inflammation and infections.
It is important to handle 2,4-DIIODO-6-METHYLBENZENAMINE with care due to its toxic nature if ingested or inhaled, and its potential to cause skin and eye irritation upon contact. Proper safety measures should be taken during its use in any application.

Upstream product

• 13194-68-8 4-iodo-2-methylaniline 
• 95-53-4 o-toluidine 

Downstream Products

• 89677-86-1 1,2,5-triiodo-3-methylbenzene 

Relevant articles and documents

Halogenation Using Quaternary Ammonium Polyhalides. VII. Iodination of Aromatic Amines by Use of Benzyltrimethylammonium Dichloroiodate(1-)

The reaction of aromatic amines with benzyltrimethylammonium dichloroiodate(1-) in dichloromethane-methanol in the presence of calcium carbonate powder for several hours at room temperature gave selectively iodo-substituted aromatic amines in good yields.

Isothiourea-Catalyzed Atroposelective N-Acylation of Sulfonamides

We report herein an atroposelective N-acylation of sulfonamides using a commercially available isothiourea catalyst, (S)-HBTM, with a simple procedure. The N-sulfonyl anilide products can be obtained in good to high enantiopurity, which represents a new axially chiral scaffold. The application of the product as a chiral iodine catalyst is also demonstrated for the asymmetric α-oxytosylation of propiophenone.

A mild and convenient synthesis of 1,2,3-triiodoarenes via consecutive iodination/diazotization/iodination strategy

A mild and convenient synthesis of 1,2,3-triiodoarenes has been developed. This method consists of two steps which can be performed on multigram scale with moderate to excellent yields. This report discloses a practical synthesis of 1,2,3-triiodoarenes and 1,2,3-trihaloarenes that is general in scope, operationally simple, scalable, and is easy to workup and to purify. We also report the first regioselective transmetalation reaction of 1,2,3-triiodoarenes to provide ortho-diiodoaryl derivatives, which are useful building blocks and indeed are hard to make by other means. CSIRO 2013.

The synthesis of novel iodinated iminodiacetic acid analogues as hepatobiliary imaging agents

The synthesis and characterization of N-[2-[[4-iodo-2,6-bis(1-methylethyl) phenyl]amino]-2-oxoethyl]-N-(carboxymethyl)glycine and N-[2-[(4-iodo-2,6- diethylphenyl)amino]-2-oxoethyl]-N-(carboxymethyl)glycine is presented, as well as a modified and improved