118025-42-6

Basic information

• Product Name: ethyl {2-[4-(1,4-dioxaspiro[4.5]dec-6-ylmethyl)phenoxy]ethyl}carbamate
• Synonyms: carbamic acid, N-[2-[4-(1,4-dioxaspiro[4.5]dec-6-ylmethyl)phenoxy]ethyl]-, ethyl ester; ethyl N-(2-(4-((2,2-(ethylenedioxy)cyclohexyl)methyl)phenoxy)ethyl)carbamate
• CAS NO: 118025-42-6
• Molecular Formula: C₂₀H₂₉NO₅
• Molecular Weight: 363.448
• Mol File: 118025-42-6.mol

Chemical Properties

• Boiling Point: 525.4°C at 760 mmHg
• Flash Point: 271.6°C
• Density: 1.16g/cm³
• Vapor Pressure: 3.92E-11mmHg at 25°C
• Refractive Index: 1.543
• CAS DataBase Reference: ethyl {2-[4-(1,4-dioxaspiro[4.5]dec-6-ylmethyl)phenoxy]ethyl}carbamate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl {2-[4-(1,4-dioxaspiro[4.5]dec-6-ylmethyl)phenoxy]ethyl}carbamate(118025-42-6)
• EPA Substance Registry System: ethyl {2-[4-(1,4-dioxaspiro[4.5]dec-6-ylmethyl)phenoxy]ethyl}carbamate(118025-42-6)

Safety Data

• Hazardous Substances Data: 118025-42-6(Hazardous Substances Data)

Upstream product

• 6329-26-6 ethyl N-(2-chloroethyl)carbamate 
• 80826-41-1 2-(4-hydroxybenzyl)-1-cyclohexanone ethylene acetal 
• 120647-24-7 ethyl N-{2-{4-[(2-oxocyclohexyl)methyl]phenyloxy}ethyl}carbamate 
• 107-21-1 ethylene glycol 
• 22081-10-3 2-(4-Hydroxybenzyl)-1-cyclohexanone 
• 155854-14-1 2-<4-(2-aminoethoxy)benzyl>cyclohexan-1-one 
• 116026-78-9 2-<4-(2-bromoethoxy)benzyl>-1-cyclohexanone 

Relevant articles and documents

Carbamate series of juvenoids: Variation of the O-alkyl substituent

By changing the O-alkyl substituents of the carbamate moiety of alkyl N-{2-{4-[(2-oxocyclohexyl)methyl]phenoxy}ethyl}carbamates and subsequent transformation of the oxo group in the cyclohexyl substituent, the juvenoids 1-20 were synthesized (Scheme). The methyl (1-4), propyl (9-12), isopropyl (13-16), and prop-2-ynylcarbamates (17-20) were subjected to biological screening on several non-related insect species (Tenebrio molitor, Galleria mellonella, Dysdercus cingulatus, and Pyrrhocoris apterus). Some of the juvenoids showed high biological activity and excellent selectivity with respect to target insect species (Table 2).

PREPARATION OF CARBAMATE DERIVATIVES OF 2-(4-HYDROXYBENZYL)-1-CYCLOHEXANONE WITH A JUVENOID ACTIVITY

The synthesis of four carbamate derivatives of 2-(4-hydroxybenzyl)-1-cyclohexanone displaying a juvenilizing effect in insects is described.The substances prepared have a greater stability and activity than their carba-analogues prepared earlier.