Synthesis and pp60c-Src tyrosine kinase inhibitory activities of novel indole-3-imine and amine derivatives substituted at N1 and C5
A series of novel 1,3,5-trisubstituted indole derivatives, namely, N-benzyl 5-phenyl indole-3-imine, N-benzyl-5-(p-fluorophenyl)indole-3-imine and their corresponding amine congeners, were designed and synthesized as pp60 c-Src tyrosine kinase
Structure-activity evaluation of n-benzyl-5-substituted indole-3-imine derivatives and their amine congeners as bovine testicular hyaluronidase (BTH) inhibitor
With the aim to overcome the lack of potent and selective Hyaluronidases (Hyals) inhibitors, we have tested new 1, 3 and 5 substituted indole derivatives for the inhibition of bovine testicular hyaluronidases (BTH) in a stains-all assay at pH 7 and in a M
Oelgen,Kaessler,Kilic Kurt,Jose
p. 685 - 690
(2012/04/05)
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