Toward the improvement of the tandem halide displacement/amide coupling spiro-cyclization as a new route to γ-lactam and pyrroloisoquinoline templates
Two efficient and rapid accesses to spiro-oxindole entities bearing an imide function were presented, and their performance was compared. The key components are N-substituted α-bromoacetamides to reach these derivatives in tandem process. The resulting sp
Allous, Iyad,Comesse, Sébastien,Berke?, Du?an,Alkyat, Amar,Da?ch, Adam
scheme or table
p. 4411 - 4415
(2009/10/26)
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