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118267-18-8

N-DEMETHYLROXITHROMYCIN is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 118267-18-8 Structure

  • Basic information

    1. Product Name: N-DEMETHYLROXITHROMYCIN
    2. Synonyms: N-DEMETHYLROXITHROMYCIN;(9E)-9-[O-[(2-Methoxyethoxy)Methyl]oxiMe]-N-deMethyl ErythroMycin;(E)-N-DeMethylroxithroMycin;RU 44981;Roxithromycin Impurity F
    3. CAS NO:118267-18-8
    4. Molecular Formula: C40H74N2O15
    5. Molecular Weight: 823.01996
    6. EINECS: N/A
    7. Product Categories: Chiral Reagents;Intermediates & Fine Chemicals;Metabolites & Impurities;Pharmaceuticals;Chiral Reagents, Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals
    8. Mol File: 118267-18-8.mol

  • Chemical Properties

    1. Melting Point: 96-98°C
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: -20?C Freezer
    8. Solubility: Chloroform (Slightly), Methanol (Slightly)
    9. CAS DataBase Reference: N-DEMETHYLROXITHROMYCIN(CAS DataBase Reference)
    10. NIST Chemistry Reference: N-DEMETHYLROXITHROMYCIN(118267-18-8)
    11. EPA Substance Registry System: N-DEMETHYLROXITHROMYCIN(118267-18-8)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 118267-18-8(Hazardous Substances Data)

118267-18-8 Usage

Chemical Properties

Off-White Solid

Uses

A metabolite of Roxithromycin (R700850).

Check Digit Verification of cas no

The CAS Registry Mumber 118267-18-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,8,2,6 and 7 respectively; the second part has 2 digits, 1 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 118267-18:
(8*1)+(7*1)+(6*8)+(5*2)+(4*6)+(3*7)+(2*1)+(1*8)=128
128 % 10 = 8
So 118267-18-8 is a valid CAS Registry Number.

118267-18-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 15, 2017

Revision Date: Aug 15, 2017

1.Identification

1.1 GHS Product identifier

Product name N-Demethyl Roxithromycin

1.2 Other means of identification

Product number -
Other names (3R,4S,5S,6R,7R,9R,10E,11S,12R,13S,14R)-14-ethyl-7,12,13-trihydroxy-4-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-6-[(2S,3R,4S,6R)-3-hydroxy-6-methyl-4-(methylamino)oxan-2-yl]oxy-10-(2-methoxyethoxymethoxyimino)-3,5,7,9,11,13-hexamethyl-o

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:118267-18-8 SDS

118267-18-8Upstream product

118267-18-8Downstream Products

118267-18-8Relevant articles and documents

MODULATION OF IMMUNE RESPONSES BY ADMINISTRATION OF ROXITHROMYCIN OR ITS DERIVATIVE

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Page/Page column 51-53, (2009/04/25)

Provided are compounds of formula (III) useful for modulation of immune responses, compositions comprising the compounds, and methods of use of such compositions for treating diseases or disorders involving an immune response. In certain embodiments, the compounds are useful for the treatment of diseases or disorders associated with transendothelial migration of T cells and activated T cells, and proinflammatory cytokine production from T cells and macrophages. Diseases or disorders that can be treated include arthritic and rheumatic disorders, such as rheumatoid arthritis.

MACROLIDE COMPOUNDS AND METHODS OF MAKING AND USING THE SAME

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Page/Page column 112, (2008/12/07)

The present invention provides amide containing macrocyclic compounds useful as therapeutic agents. More particularly, these compounds are useful as anti-infective, anti-proliferative, anti-inflammatory, and prokinetic agents.

TRIAZOLE COMPOUNDS AND METHODS OF MAKING AND USING THE SAME

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Page/Page column 307-308, (2008/06/13)

The present invention provides triazole macrocyclic compounds useful as therapeutic agents. More particularly, these compounds are useful as anti-infective, antiproliferative, anti-inflammatory, and prokinetic agents.

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