Expeditious construction of quinazolines via Bronsted acid-induced C-H activation: Further extension of "tert-amino effect"
A simple method for the synthesis of quinazolines was developed by exploiting the "tert-amino effect." A catalytic amount of Br0nsted acid (TsOH·H2O) worked as an effective activator for the concise construction of a quinazoline framework from o-formylaniline and amine. Copyright