118537-23-8Relevant articles and documents
Asymmetric Syntheses of Diastereomerically and Enantiomerically Pure (2R,3S)-threo-3-Arylserine Methyl Esters by the Bislactim Ether Method Asymmetric Synthesis of Chloramphenicol
Schoellkopf, Ulrich,Beulshausen, Tessa
, p. 223 - 226 (2007/10/02)
The titanium derivative 3 of the bislactim ether 1 of cyclo(-L-Val-Gly-) reacts with arylaldehydes 4 highly diastereoselectively to give the syn-addition products of type 5.On hydrolysis, these yield besides methyl L-valinate (6) and small amounts of the