1185883-39-9

Basic information

• Product Name: C₄₀H₃₆F₂N₂O₅
• Synonyms: C₄₀H₃₆F₂N₂O₅
• CAS NO: 1185883-39-9
• Molecular Weight: 662.733
• Mol File: 1185883-39-9.mol

Chemical Properties

• CAS DataBase Reference: C₄₀H₃₆F₂N₂O₅(CAS DataBase Reference)
• NIST Chemistry Reference: C₄₀H₃₆F₂N₂O₅(1185883-39-9)
• EPA Substance Registry System: C₄₀H₃₆F₂N₂O₅(1185883-39-9)

Safety Data

• Hazardous Substances Data: 1185883-39-9(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
C₄₀H₃₆F₂N₂O₅ is used as a pharmaceutical compound for its potential medicinal properties. The presence of nitrogen and oxygen atoms may allow for the formation of amines or amides, which are common in drug molecules. Additionally, the fluorine atoms could contribute to the compound's bioavailability and pharmacokinetic properties, making it a promising candidate for drug development.
Used in Agrochemical Industry:
In the agrochemical sector, C₄₀H₃₆F₂N₂O₅ may serve as an active ingredient in pesticides or herbicides. The fluorinated nature of the compound could enhance its stability and effectiveness in controlling pests or weeds, while the nitrogen and oxygen atoms could provide the necessary reactivity for biological activity.
Used in Materials Science:
C₄₀H₃₆F₂N₂O₅ is used as a material in the development of advanced materials. The complex structure of the compound, with its various atoms and potential functional groups, could be utilized to create new materials with unique properties, such as improved strength, flexibility, or thermal stability, for use in various applications, including electronics, aerospace, or automotive industries.

Upstream product

• 954109-20-7 (S)-3-{(R)-2-[(S)-[4-(benzyloxy)phenyl][(4-fluorophenyl)amino]methyl]-4-[2-(4-fluorophenyl)[1,3]dioxolan-2-yl]butanoyl}-4-phenyl-oxazolidin-2-one 
• 4397-53-9 p-benzyloxybenzaldehyde 
• 100-44-7 benzyl chloride 
• 123-08-0 4-hydroxy-benzaldehyde 
• 70627-52-0 4-benzyloxybenzylidene-N-(4-fluoro)phenylanisidine 
• 189028-95-3 (4S)-3-[(5S)-5-(4-fluorophenyl)-5-hydroxypentanoyl]-4-phenyl-1,3-oxazolidine-2-one 
• 1185883-43-5 C₄₀H₃₄F₂N₂O₅ 

Relevant articles and documents

METHOD FOR PRODUCING EZETIMIBE AND INTERMEDIATE THEREOF

PROBLEM TO BE SOLVED: To provide a method for producing ezetimibe that is a cholesterol-lowering agent. SOLUTION: The present invention provides a method for producing ezetimibe (I) that generates intermediate (M1) and eliminates a protecting group. [R1 is a benzyl group and others, R2 is an ether protecting group such as a silyl ether protecting group]. SELECTED DRAWING: None COPYRIGHT: (C)2016,JPOandINPIT

INTERMEDIATES FOR THE PREPARATION OF (3R, 4S)-1-(4-FLUOROPHENYL)-3-[(3S)-3-(4-FLUOROPHENYL)-3-HYDROXYPROPYL)]-4-(4-HYDROXYPHENYL)-2-AZETIDINONE

A method for the preparation of (S)-alcohol oxazolidides of general formula II, in which PG represents hydrogen or a hydroxyl protecting group, such as trimethylsilyl, tert-butyldimethylsilyl, benzyloxycarbonyl, tert-butoxycarbonyl, benzyl, benzhydryl or

INTERMEDIATES FOR THE PREPARATION OF (3R, 4S) -1- (4-FLUOROPHENYL) -3- [ (3S) -3- (4-FLUOROPHENYL) -3-HYDROXYPROPYL) ] -4- (4-HYDROXYPHENYL) -2-AZETIDINONE

A method for the preparation of (S)-alcohol oxazolidides of general formula II, in which PG represents hydrogen or a hydroxyl protecting group, such as trimethylsilyl, tert-butyldimethylsilyl, benzyloxycarbonyl, tert-butoxycarbonyl, benzyl, benzhydryl or trityl, in which a ketal oxazolidide of general formula III, where PG has the same meaning as above and R means an alkyl with 1-4 carbon atoms, linear or branched, such as methyl, ethyl, isopropyl or butyl, or R+R together represents a divalent alkyl, or substituted with 1 or 2 alkyl groups, e.g. 1,2-ethylene, 1,2-propylene, 1,2-butylene, 1,3-propylene or 2,2-dimethyl-l,3- propylene, is deprotected by the action of acidic reagents in a mixture of water and a water- miscible solvent in the temperature range of 0 to 100 °C (stage A), and the obtained ketone oxazolidide of general IV, in which PG has the same meaning as above, is reduced with asymmetrical reagents in an inert organic solvent in the temperature range of -30 to +40 °C (stage B).