cas 1187-87-7, 5-Methyl-3-methylene-2-hexanone | Articles data ｜lookchem

Welcome to LookChem.com Sign In|Join Free

Article Database

Home > CAS Article list >
1187-87-7

Articles about 1187-87-7Total 2 be found

Article title
Article abstract
Author
Journal number and time
Download

Real-Time Monitoring of Solid-Liquid Slurries: Optimized Synthesis of Tetrabenazine
Solid-liquid slurries are vital and increasingly prevalent in the pharmaceutical and chemical industries. Despite the importance of these heterogeneous systems, process control and optimization are fundamentally hindered by a lack of compatible real-time analytical techniques. We present herein an online HPLC monitoring platform enabling access to real-time compositional information on slurries. We demonstrate the system by investigating the heterogeneous synthesis reaction of tetrabenazine. Furthermore, we integrated our online HPLC platform with the orthogonal monitoring techniques of a pH probe and a microscopic imaging probe to provide additional mechanistic insight. These combined insights enable the optimization of tetrabenazine synthesis in terms of reaction time, byproduct formation, and diastereomeric purity of the final product.
Sato, Yusuke,Liu, Junliang,Kukor, Andrew J.,Culhane, Jeffrey C.,Tucker, John L.,Kucera, David J.,Cochran, Brian M.,Hein, Jason E.
p. 14069 - 14078
(2021/07/26)

β-Silylcarbonyl Compounds as Masked Enones
β-Trimethylsilylketones and lactones can be brominated (3)->(4) and desilylbrominated (4)->(5) specifically to place a double bond between the carbonyl group and the β-carbon atom to which the silicon had originally been bound.The silyl group therefore is a base- and acid stable group masking the α,β-unsaturation of enones.Several α-methylene-ketones and -lactones have been prepared in this way.With ketones, the bromination step seems always to introduce bromine mainly or exclusively at the α-position on that side of the ketone on which the β-silyl group is placed, regardless of whether it is more or the less substituted α-position.
Fleming, Ian,Goldhill, Jon
p. 1493 - 1498
(2007/10/02)

More Articles about upstream products of 1187-87-7

More Articles about downstream products of 1187-87-7

Chemical Properties

Boiling Point: 170 °C at 760 mmHg
Flash Point:54.1 °C
Density: 0.824 g/cm³
Vapor Pressure: 1.5mmHg at 25°C
Refractive Index: 1.419
PSA: 17.07000
LogP: 2.17770

Show more

Global suppliers and manufacturers of 1187-87-7total 39 suppliers on LookChem

Company Name
Business Type
Min Order
FOB Price
Main Products
Contact

Henan Allgreen Chemical Co.,Ltd
Business Type:Manufacturers
Min Order:1 Kilogram
FOB Price:No Data
Main Products:34
Country:

Dayang Chem (Hangzhou) Co.,Ltd.
Business Type:Lab/Research institutions
Min Order:1 Kilogram
FOB Price:USD $ 2.0-2.0 / Kilogram
Main Products:982
Country:

Zhuozhou Wenxi import and Export Co., Ltd
Business Type:Trading Company
Min Order:1 Kilogram
FOB Price:USD $ 139.0-210.0 / Kilogram
Main Products:1
Country:

Shaanxi BLOOM TECH Co.,Ltd
Business Type:Lab/Research institutions
Min Order:1 Gram
FOB Price:No Data
Main Products:79
Country:

Hebei yanxi chemical co.,LTD.
Business Type:Manufacturers
Min Order:1 Metric Ton
FOB Price:USD $ 1.0-2.0 / Metric Ton
Main Products:82
Country:

Shanghai Upbio Tech Co.,Ltd
Business Type:Lab/Research institutions
Min Order:1 Kilogram
FOB Price:No Data
Main Products:89
Country:

Changchun JuShengyuan Import and Export Trading Co.,Ltd
Business Type:Trading Company
Min Order:100 Gram
FOB Price:No Data
Main Products:63
Country:

Henan Wentao Chemical Product Co., Ltd.
Business Type:Lab/Research institutions
Min Order:No Data
FOB Price:No Data
Main Products:44
Country:

Qingdao Beluga Import and Export Co., LTD
Business Type:Lab/Research institutions
Min Order:1 Gram
FOB Price:No Data
Main Products:113
Country:

Changchun Artel lmport and Export trade company
Business Type:Trading Company
Min Order:10 Gram
FOB Price:No Data
Main Products:66
Country:

Shandong Hanjiang Chemical Co., Ltd.
Business Type:Lab/Research institutions
Min Order:1 Kilogram
FOB Price:No Data
Main Products:77
Country:

Hebei Guanlang Biotechnology Co., Ltd.
Business Type:Trading Company
Min Order:1 Kilogram
FOB Price:USD $ 1.0-1.0 / Kilogram
Main Products:76
Country:

Hangzhou J&H Chemical Co., Ltd.
Business Type:Lab/Research institutions
Min Order:No Data
FOB Price:No Data
Main Products:46
Country:

Zibo Hangyu Import&Export Co., Ltd
Business Type:Lab/Research institutions
Min Order:1 Kilogram
FOB Price:USD $ 100.0-100.0 / Kilogram
Main Products:246
Country:

GIHI CHEMICALS CO.,LIMITED
Business Type:Lab/Research institutions
Min Order:No Data
FOB Price:No Data
Main Products:47
Country:

Hangzhou Dingyan Chem Co., Ltd
Business Type:Manufacturers
Min Order:No Data
FOB Price:No Data
Main Products:95
Country:

Shanghai Run-Biotech Co., Ltd.
Business Type:Trading Company
Min Order:No Data
FOB Price:No Data
Main Products:83
Country:

Antimex Chemical Limied
Business Type:Lab/Research institutions
Min Order:No Data
FOB Price:No Data
Main Products:163
Country:

Hangzhou Fandachem Co.,Ltd
Business Type:Other
Min Order:No Data
FOB Price:No Data
Main Products:52
Country:

Henan Kanbei Chemical Co.,LTD
Business Type:Lab/Research institutions
Min Order:No Data
FOB Price:No Data
Main Products:62
Country:

Post a RFQ

Cas No.:

Product Name:

Quantity:

Email:

Company name:

Valid Period:

Detailed Requirements:

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 1187-87-7

About us - Payment - Contact us - Links - Help Center - Disclaimer
SiteMap | Manufacturers | VIP Product | Suppliers | CAS | New CAS | Cas Database | Article Data | Chemical Catalog | Product Name

©2008 LookChem.com,License:ICP NO.:Zhejiang16009103 complaints:service@lookchem.com
[Hangzhou]86-571-87562588,87562561,87562573 Our Legal adviser: Lawyer