Development and application of a new general method for the asymmetric synthesis of (E)-(2-En-3-ynyl)-amines
The first direct approach for the asymmetric synthesis of (E)-2-arylidene-1,4-diphenylbut-3-yn-1-amines by addition of alkynylzinc to chiral N-tert-butylsulfinylimines is reported with excellent diastereoselectivity and good yield. This asymmetric additio