- SUBSTITUTED DIHYDRO-ISOINDOLONES USEFUL IN TREATING KINASE DISORDERS
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The present invention is directed to novel substituted dihydro-isoindolone compounds of formula (I): and forms thereof, wherein Ring A, X3, R1, R2, R3, R4 and R6 are as herein defined, and their synthesis and use as protein kinase inhibitors and interactions thereof.
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Page/Page column 57
(2008/06/13)
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- 4-Alkoxy-6-alkyl-2-pyrones as Precursors for 4-Alkoxy-6-alkyl-2-aminobenzoic Acid Derivatives
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4-Alkoxy-6-alkyl-2-pyrones undergo Diels-Alder reaction with dimethyl acetylenedicarboxylate to give dimethyl 4-alkoxy-6-alkylphthalates, which can be converted into 4-alkoxy-6-alkyl-2-aminobenzoic esters via a simple two-step sequence.
- Tam, Tim Fat,Coles, Peter
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p. 383 - 386
(2007/10/02)
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