MK2 INHIBITORS, SYNTHESIS THEREOF, AND INTERMEDIATES THERETO
The present invention provides methods of preparing a MK2 inhibitor, and intermediates related thereto.
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(2018/10/19)
MK2 INHIBITORS AND USES THEREOF
The present invention provides compounds, compositions thereof, and methods of using the same.
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(2016/04/09)
MK2 INHIBITORS AND USES THEREOF
The present invention provides compounds, compositions thereof, and methods of using the same.
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(2014/10/03)
INHIBITORS OF VIRAL REPLICATION, THEIR PROCESS OF PREPARATION AND THEIR THERAPEUTICAL USES
The present invention relates to compounds, their use in the treatment or the prevention of viral disorders, including HIV.
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(2012/11/06)
INHIBITORS OF VIRAL REPLICATION, THEIR PROCESS OF PREPARATION AND THEIR THERAPEUTICAL USES
The present invention relates to compounds of formula (1) as claimed in claim 1, their use in the treatment or the prevention of viral disorders, including HIV. (Formula I)
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(2012/10/18)
Benzothiophene inhibitors of MK2. Part 2: Improvements in kinase selectivity and cell potency
Optimization of kinase selectivity for a set of benzothiophene MK2 inhibitors provided analogs with potencies of less than 500 nM in a cell based assay. The selectivity of the inhibitors can be rationalized by examination of X-ray crystal structures of in
Anderson, David R.,Meyers, Marvin J.,Kurumbail, Ravi G.,Caspers, Nicole,Poda, Gennadiy I.,Long, Scott A.,Pierce, Betsy S.,Mahoney, Matthew W.,Mourey, Robert J.,Parikh, Mihir D.
scheme or table
p. 4882 - 4884
(2010/04/26)
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