118850-71-8 Usage
Uses
Used in Pharmaceutical Industry:
ANTI-INFLAMMATORY PEPTIDE 1 is used as an anti-inflammatory agent for its potential to alleviate pain and stiffness in conditions like arthritis by reducing inflammation.
Used in Immunology Research:
This peptide is utilized as an immune response modulator for its capacity to regulate the immune system and potentially decrease the production of pro-inflammatory molecules, which can be crucial in managing inflammatory diseases.
Used in Drug Development:
ANTI-INFLAMMATORY PEPTIDE 1 serves as a candidate for the development of new therapeutics aimed at treating various inflammatory conditions, pending further understanding of its mechanisms of action and clinical validation.
Check Digit Verification of cas no
The CAS Registry Mumber 118850-71-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,8,8,5 and 0 respectively; the second part has 2 digits, 7 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 118850-71:
(8*1)+(7*1)+(6*8)+(5*8)+(4*5)+(3*0)+(2*7)+(1*1)=138
138 % 10 = 8
So 118850-71-8 is a valid CAS Registry Number.
InChI:InChI=1/C45H82N12O14S2/c1-24(2)21-31(42(67)54-32(22-35(60)61)43(68)56-33(23-58)45(70)71)55-44(69)36(25(3)4)57-41(66)28(12-8-10-18-47)52-38(63)27(11-7-9-17-46)51-40(65)30(16-20-73-6)53-39(64)29(13-14-34(49)59)50-37(62)26(48)15-19-72-5/h24-33,36,58H,7-23,46-48H2,1-6H3,(H2,49,59)(H,50,62)(H,51,65)(H,52,63)(H,53,64)(H,54,67)(H,55,69)(H,56,68)(H,57,66)(H,60,61)(H,70,71)/t26-,27-,28?,29-,30?,31?,32-,33-,36-/m0/s1
118850-71-8Relevant articles and documents
LIPOXYGENASE INHIBITOR PEPTIDES AND THEIR USE
-
Page/Page column 23, (2008/06/13)
The present invention is in the field of enzyme inhibition. In particular it relates to peptide inhibitors for lipoxygenases. The lipoxygenase peptide inhibitors of have the potential to be used as therapeutic drugs as well as food preservatives.
Studies on the anti-phospholipase A2 and anti-inflammatory activities of a uteroglobin fragment and related peptides
Marastoni,Scaranari,Romuldi,Donatini,Ferri,Tomatis
, p. 997 - 1000 (2007/10/02)
The nonapeptide antiflammin P1 (H-Met-Gln-Met-Lys-Lys-Val-Leu-Asp-Ser-OH), its isoAsp8 analogue and the corresponding aminosuccinyl peptide were prepared, characterized and tested for inhibition of phospholipase A2 (PLA2) in vitro and for anti-inflammatory activity in vivo under assay conditions recently recommended. All peptides are devoid of PLA2 inhibitory and anti-inflammatory activity.
Studies of anti-phospholipase A2 and anti-inflammatory activites of a synthetic nonapeptide from uteroglobin
Marastoni,Salvadori,Balboni,Scaranari,Santagada,Romualdi,Ferri,Tomatis
, p. 240 - 243 (2007/10/02)
The nonapeptide H-Met-Gln-Met-Lys-Lys-Val-Leu-Asp-Ser-OH (antiflammin), corresponding to a high amino acid similarity region of uteroglobin was prepared by solution and solid phase synthesis. The peptide do not inhibit pancreatic phospolipase A2/sub