1188522-81-7Relevant articles and documents
Synthesis and characterization of RNA containing a rigid and nonperturbing cytidine-derived spin label
Hoebartner, Claudia,Sicoli, Giuseppe,Wachowius, Falk,Gophane, Dnyaneshwar B.,Sigurdsson, Snorri Th.
, p. 7749 - 7754 (2012/11/07)
The nitroxide-containing nucleoside Cm is reported as the first rigid spin label for paramagnetic modification of RNA by solid-phase synthesis. The spin label is well accommodated in several RNA secondary structures as judged by its minor effect on the thermodynamic stability of hairpin and duplex RNA. Electron paramagnetic resonance (EPR) spectroscopic characterization of mono-, bi-, and trimolecular RNA structures shows that Cm will be applicable for advanced EPR studies to elucidate structural and dynamic aspects of folded RNA.
NUCLEIC ACID CHEMICAL MODIFICATIONS
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Page/Page column 240-241, (2010/09/18)
he present invention provides nucleosides of formula (1) and oligonucleotides comprising at least on nucleoside of formula (2): Another aspect of the invention relates to a method of inhibiting the expression of a gene in cell, the method comprising (a) c
NON-NATURAL RIBONUCLEOTIDES, AND METHODS OF USE THEREOF
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, (2009/10/22)
One aspect of the present invention relates to modified nucleosides and oligonucleotides comprising such modified nucleosides. Another aspect of the invention relates to a method of inhibiting the expression of a gene in call, the method comprising (a) co