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CL-82198 is a selective inhibitor of human collagenase-3, also known as matrix metalloproteinase-13 (MMP-13). It is a synthetic compound designed to target and inhibit the activity of this specific enzyme, which plays a crucial role in the degradation of collagen in various physiological and pathological processes.

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  • N-(4-morpholin-4-ylbutyl)-1-benzofuran-2-carboxamide;hydrochloride

    Cas No: 1188890-36-9

  • USD $ 1.9-2.9 / Gram

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  • 1188890-36-9 Structure
  • Basic information

    1. Product Name: CL-82198
    2. Synonyms: CL-82198
    3. CAS NO:1188890-36-9
    4. Molecular Formula: C17H23ClN2O3
    5. Molecular Weight: 338.82912
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1188890-36-9.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: CL-82198(CAS DataBase Reference)
    10. NIST Chemistry Reference: CL-82198(1188890-36-9)
    11. EPA Substance Registry System: CL-82198(1188890-36-9)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1188890-36-9(Hazardous Substances Data)

1188890-36-9 Usage

Uses

Used in Pharmaceutical Industry:
CL-82198 is used as a therapeutic agent for the treatment of conditions associated with excessive MMP-13 activity. Its selective inhibition of collagenase-3 makes it a potential candidate for managing diseases characterized by abnormal collagen degradation, such as osteoarthritis and other connective tissue disorders.
Used in Research Applications:
In addition to its potential clinical use, CL-82198 serves as a valuable research tool for studying the role of MMP-13 in various biological processes. By selectively inhibiting this enzyme, researchers can gain insights into its function and the consequences of its dysregulation, ultimately contributing to a better understanding of the underlying mechanisms of related diseases and the development of targeted therapies.

Check Digit Verification of cas no

The CAS Registry Mumber 1188890-36-9 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,8,8,8,9 and 0 respectively; the second part has 2 digits, 3 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 1188890-36:
(9*1)+(8*1)+(7*8)+(6*8)+(5*8)+(4*9)+(3*0)+(2*3)+(1*6)=209
209 % 10 = 9
So 1188890-36-9 is a valid CAS Registry Number.

1188890-36-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name N-[4-(4-Morpholinyl)butyl]-1-benzofuran-2-carboxamide hydrochlori de (1:1)

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1188890-36-9 SDS

1188890-36-9Upstream product

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