118949-63-6

Basic information

• Product Name: 2,6-Bis[(4S)-4-tert-butyloxazolin-2-yl]pyridine
• Synonyms: 2,6-BIS[(4S)-4-TERT-BUTYL-2-OXAZOLIN-2YL]PYRIDINE;2,6-BIS[(4S)-4-TERT-BUTYLOXAZOLIN-2-YL]PYRIDINE;2,6-Bis[(4S)-4-(1,1-dimethylethyl)-4,5-dihydro-2-oxazolyl]pyridine;2,6-Bis[(4S)-4-ter-butyloxazolin-2-yl]-pyridine;2,6-Bis((S)-4-(tert-butyl)-4,5-dihydrooxazol-2-yl)pyridine;2,6-Bis[(4S)-4-tert-butyloxazolin-2-yl]pyridine,99%e.e.;2,6-Bis[(4S)-4-tert-butyloxazolin-2-yl]pyridine, 98%, (99% ee)
• CAS NO: 118949-63-6
• Molecular Formula: C19H27N3O2
• Molecular Weight: 329.44
• Product Categories: Amino Alcohols & Deriv.;CHIRAL CHEMICALS
• Mol File: 118949-63-6.mol

Chemical Properties

• Boiling Point: 467.131 °C at 760 mmHg
• Flash Point: 236.313 °C
• Appearance: Light yellow liquid
• Density: 1.15
• Vapor Pressure: 1.87E-08mmHg at 25°C
• Refractive Index: 1.575
• Storage Temp.: 2-8°C
• PKA: 3.91±0.70(Predicted)
• CAS DataBase Reference: 2,6-Bis[(4S)-4-tert-butyloxazolin-2-yl]pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 2,6-Bis[(4S)-4-tert-butyloxazolin-2-yl]pyridine(118949-63-6)
• EPA Substance Registry System: 2,6-Bis[(4S)-4-tert-butyloxazolin-2-yl]pyridine(118949-63-6)

Safety Data

• Hazardous Substances Data: 118949-63-6(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
2,6-Bis[(4S)-4-tert-butyloxazolin-2-yl]pyridine is used as a chiral ligand in asymmetric catalysis for the synthesis of pharmaceuticals. Its enhanced steric hindrance and ability to create asymmetric centers during chemical reactions make it highly valuable in the precise arrangement of atoms in complex molecules, leading to the development of innovative and effective drugs.
Used in Chemical Synthesis:
In the field of chemical synthesis, 2,6-Bis[(4S)-4-tert-butyloxazolin-2-yl]pyridine is used as a chiral catalyst to facilitate the formation of enantiomerically pure compounds. Its unique structure and steric properties enable the selective formation of specific enantiomers, which is crucial for the development of high-quality and efficient chemical products.
Used in Research and Development:
2,6-Bis[(4S)-4-tert-butyloxazolin-2-yl]pyridine is also utilized in research and development for the exploration of new catalytic processes and the discovery of novel asymmetric reactions. Its unique properties and applications in chiral catalysis make it an essential tool for chemists working on the development of new synthetic methods and the synthesis of complex molecules with potential applications in various industries.

InChI:InChI=1/C19H27N3O2/c1-18(2,3)14-10-23-16(21-14)12-8-7-9-13(20-12)17-22-15(11-24-17)19(4,5)6/h7-9,14-15H,10-11H2,1-6H3/t14-,15-/m1/s1

Upstream product

• 2893-33-6 pyridine-2,6-dinitrile 
• 112245-13-3 (S)-tert-leucinol 
• 3739-94-4 2,6-Pyridinedicarbonyl dichloride 
• 499-83-2 Pyridine-2,6-dicarboxylic acid 

Relevant articles and documents

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