Yeast-Mediated Reduction of N-Substituted Acetoacetamides. Improvement of Conversion by Immobilization
N-Ethylacetoacetamide and acetoacetanilide were enantioselectively converted into the corresponding (S)-3-hydroxy compounds by alginate- or polyurethane-immobilized baker's yeasts, while whithout immobilization the yield of the yeast-mediated reaction was very low.