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1191429-14-7

(S)-N-FMoc-2-(6'-azido)alanine is a chemical compound with a molecular formula of C20H21N5O4. It is a derivative of alanine, an α-amino acid that serves as a building block for proteins. (S)-N-FMoc-2-(6'-azido)alanine features a fluorenylmethyloxycarbonyl (FMoc) protecting group on the amine group and a 6'-azido group on the α-carbon of alanine. The azido group endows this compound with unique reactivity for bioconjugation and click chemistry, allowing selective reactions with terminal alkynes or strained cyclooctynes. (S)-N-FMoc-2-(6'-azido)alanine is valuable in the development of peptide-based therapeutics and biomaterials.

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  • 1191429-14-7 Structure

  • Basic information

    1. Product Name: (S)-N-FMoc-2-(6'-azido)alanine
    2. Synonyms: (S)-N-FMoc-2-(6'-azido)alanine;(S)-N-Fmoc-2-(6'-azidohexyl)alanine;(R)-N-Fmoc-2-(6'-azido)alanine
    3. CAS NO:1191429-14-7
    4. Molecular Formula: C24H29N4O4
    5. Molecular Weight: 436.50351
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1191429-14-7.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: (S)-N-FMoc-2-(6'-azido)alanine(CAS DataBase Reference)
    10. NIST Chemistry Reference: (S)-N-FMoc-2-(6'-azido)alanine(1191429-14-7)
    11. EPA Substance Registry System: (S)-N-FMoc-2-(6'-azido)alanine(1191429-14-7)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1191429-14-7(Hazardous Substances Data)

1191429-14-7 Usage

Uses

Used in Pharmaceutical Industry:
(S)-N-FMoc-2-(6'-azido)alanine is used as a building block for the synthesis of peptide-based therapeutics. Its unique azido group allows for selective bioconjugation and click chemistry reactions, facilitating the development of novel drug candidates with improved targeting and delivery properties.
Used in Biomaterials Development:
(S)-N-FMoc-2-(6'-azido)alanine is used as a key component in the creation of biomaterials. (S)-N-FMoc-2-(6'-azido)alanine's reactivity enables the formation of stable covalent bonds with other biomolecules, allowing for the design of advanced biomaterials with tailored properties for various applications, such as tissue engineering and drug delivery systems.
Used in Bioconjugation:
(S)-N-FMoc-2-(6'-azido)alanine is used as a bioconjugation agent for the attachment of biologically active molecules to other biomolecules or surfaces. The azido group provides a reactive handle for click chemistry, enabling the formation of stable and specific conjugates with high efficiency and selectivity.
Used in Click Chemistry:
(S)-N-FMoc-2-(6'-azido)alanine is used as a reactant in click chemistry reactions, particularly the copper-catalyzed azide-alkyne cycloaddition (CuAAC). This reaction allows for the rapid and efficient formation of triazole linkages between the azido-alanine and terminal alkynes, facilitating the construction of complex molecular architectures and the modification of biomolecules with high specificity.

Check Digit Verification of cas no

The CAS Registry Mumber 1191429-14-7 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,9,1,4,2 and 9 respectively; the second part has 2 digits, 1 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 1191429-14:
(9*1)+(8*1)+(7*9)+(6*1)+(5*4)+(4*2)+(3*9)+(2*1)+(1*4)=147
147 % 10 = 7
So 1191429-14-7 is a valid CAS Registry Number.

1191429-14-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name (2R)-8-Azido-2-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-2-methyl octanoic acid

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

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More Details:1191429-14-7 SDS

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