Thienopyrroles: Synthesis, Diels-ALder Reaction, and Synthetic Utility
5H-Thienopyrrole 1a and the N-substituted derivatives 1b-h and 11-13 were synthesized by the novel retro-malonate addition reaction.Thienopyrroles readily underwent the Diels-Alder reaction with reactive dienophiles, such as N-phenylmaleimid
Sha, Chin-Kang,Tsou, Chiu-Peng
p. 2446 - 2450
(2007/10/02)
A Retro-malonate Addition Reaction: Synthesis of 3,4-Condensed Heteroaromatic Pyrroles
Treatment of bromo alkylidenemalonates (1)-(4) with ammonia or amines afforded 3,4-condensed heteroaromatic pyrroles (5)-(8) in excellent yields; benzotripyrroles (19)-(21) were synthesized by the same method.