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CAS

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1196145-66-0

2-Bromo-5-chloro-4-hydroxypyridin, also known as 5-chloro-2-bromohydroxypyridine, is a halogenated pyridine derivative with the molecular formula C5H3BrClNO. It is a white to light yellow solid that is sparingly soluble in water but soluble in organic solvents. This chemical compound is commonly used as an intermediate in the synthesis of pharmaceuticals, agrochemicals, and other organic compounds due to its potential to undergo various reactions, including nucleophilic substitution and metal-catalyzed reactions.

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  • 1196145-66-0 Structure

  • Basic information

    1. Product Name: 2-Bromo-5-chloro-4-hydroxypyridin
    2. Synonyms: 2-Bromo-5-chloro-4-hydroxypyridin;2-broMo-5-chloropyridin-4-ol;2-Bromo-5-chloro-4-hydroxypyridine
    3. CAS NO:1196145-66-0
    4. Molecular Formula: C5H3BrClNO
    5. Molecular Weight: 208
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1196145-66-0.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 2-Bromo-5-chloro-4-hydroxypyridin(CAS DataBase Reference)
    10. NIST Chemistry Reference: 2-Bromo-5-chloro-4-hydroxypyridin(1196145-66-0)
    11. EPA Substance Registry System: 2-Bromo-5-chloro-4-hydroxypyridin(1196145-66-0)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1196145-66-0(Hazardous Substances Data)

1196145-66-0 Usage

Uses

Used in Pharmaceutical Industry:
2-Bromo-5-chloro-4-hydroxypyridin is used as a key intermediate in the synthesis of various pharmaceuticals. Its unique structure and reactivity make it a valuable building block for the development of new drugs with improved therapeutic properties.
Used in Agrochemical Industry:
In the agrochemical industry, 2-Bromo-5-chloro-4-hydroxypyridin is used in the production of fungicides, herbicides, and insecticides. Its ability to effectively inhibit the growth of microorganisms and pests makes it a valuable component in the development of crop protection products.
Used in Organic Synthesis:
2-Bromo-5-chloro-4-hydroxypyridin is used as a versatile building block in organic synthesis. Its potential to undergo various reactions, such as nucleophilic substitution and metal-catalyzed reactions, allows chemists to create a wide range of organic compounds with diverse applications.

Check Digit Verification of cas no

The CAS Registry Mumber 1196145-66-0 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,9,6,1,4 and 5 respectively; the second part has 2 digits, 6 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 1196145-66:
(9*1)+(8*1)+(7*9)+(6*6)+(5*1)+(4*4)+(3*5)+(2*6)+(1*6)=170
170 % 10 = 0
So 1196145-66-0 is a valid CAS Registry Number.

1196145-66-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-bromo-5-chloro-1H-pyridin-4-one

1.2 Other means of identification

Product number -
Other names 2-Bromo-5-chloro-4-hydroxypyridine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1196145-66-0 SDS

1196145-66-0Downstream Products

1196145-66-0Relevant articles and documents

PYRIDINECARBOXAMIDES DERIVATIVES, PREPARATION PROCESS AND PHARMACEUTICAL USE THEREOF

-

Paragraph 40; 41, (2017/01/02)

The present invention relates to pyridinecarboxamides derivatives, preparation processes and pharmaceutical use thereof. Specifically, the present invention relates to pyridinecarboxamides derivatives of general formula (I) and the pharmaceutical composition, as well as their use as a therapeutic agent, especially these compounds are inhibitors of ROMK and are therefore useful in the treatment and/or prevention of hypertension and heart failure, wherein each substitute of general formula (I) is defined as the specification.

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