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1196510-34-5

C32H30F2N4O7 is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 1196510-34-5 Structure

  • Basic information

    1. Product Name: C32H30F2N4O7
    2. Synonyms:
    3. CAS NO:1196510-34-5
    4. Molecular Formula:
    5. Molecular Weight: 620.61
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1196510-34-5.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: C32H30F2N4O7(CAS DataBase Reference)
    10. NIST Chemistry Reference: C32H30F2N4O7(1196510-34-5)
    11. EPA Substance Registry System: C32H30F2N4O7(1196510-34-5)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1196510-34-5(Hazardous Substances Data)

1196510-34-5 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1196510-34-5 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,9,6,5,1 and 0 respectively; the second part has 2 digits, 3 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 1196510-34:
(9*1)+(8*1)+(7*9)+(6*6)+(5*5)+(4*1)+(3*0)+(2*3)+(1*4)=155
155 % 10 = 5
So 1196510-34-5 is a valid CAS Registry Number.

1196510-34-5Downstream Products

1196510-34-5Relevant articles and documents

Selective Nonsteroidal Glucocorticoid Receptor Modulators for the Inhaled Treatment of Pulmonary Diseases

Hemmerling, Martin,Nilsson, Stinabritt,Edman, Karl,Eirefelt, Stefan,Russell, Wayne,Hendrickx, Ramon,Johnsson, Eskil,K?rrman M?rdh, Carina,Berger, Markus,Rehwinkel, Hartmut,Abrahamsson, Anna,Dahmén, Jan,Eriksson, Anders R.,Gabos, Balint,Henriksson, Krister,Hossain, Nafizal,Ivanova, Svetlana,Jansson, Anne-Helene,Jensen, Tina J.,Jerre, Anders,Johansson, Henrik,Klingstedt, Tomas,Lepist?, Matti,Lindsj?, Martin,Mile, Irene,Nikitidis, Grigorios,Steele, John,Tehler, Ulrika,Wissler, Lisa,Hansson, Thomas

, p. 8591 - 8605 (2017/11/03)

A class of potent, nonsteroidal, selective indazole ether-based glucocorticoid receptor modulators (SGRMs) was developed for the inhaled treatment of respiratory diseases. Starting from an orally available compound with demonstrated anti-inflammatory activity in rat, a soft-drug strategy was implemented to ensure rapid elimination of drug candidates to minimize systemic GR activation. The first clinical candidate 1b (AZD5423) displayed a potent inhibition of lung edema in a rat model of allergic airway inflammation following dry powder inhalation combined with a moderate systemic GR-effect, assessed as thymic involution. Further optimization of inhaled drug properties provided a second, equally potent, candidate, 15m (AZD7594), that demonstrated an improved therapeutic ratio over the benchmark inhaled corticosteroid 3 (fluticasone propionate) and prolonged the inhibition of lung edema, indicating potential for once-daily treatment.

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